KPV research product
The KPV research product is available in New Zealand for laboratory study.
KPV is a tripeptide made of three amino acids: lysine (K), proline (P), and valine (V). It is the C-terminal fragment of alpha-MSH (alpha-melanocyte-stimulating hormone), a naturally occurring hormone with anti-inflammatory activity.
KPV keeps the short amino-acid sequence associated with alpha-MSH's anti-inflammatory activity without its pigment-producing action. Oral, topical, injectable, and nasal products use that small size in different ways.
Benefits and uses
KPV research and reported use center on inflammation in three areas:
Gut healing and inflammatory bowel conditions. In a cell and mouse colitis study, KPV entered intestinal cells through the PepT1 transporter and reduced inflammatory signaling. Oral KPV also reduced inflammation in two mouse models.
Immune modulation. It downregulates inflammatory signaling broadly, which is why it is studied as a general anti-inflammatory rather than for one tissue alone.
Skin inflammation. Laboratory work includes human keratinocytes and three-dimensional skin models. A 2025 study examined oxidative stress, inflammatory signaling, and cell survival after particulate exposure.
About this research peptide
Every peptide in our catalogue is supplied as a lyophilised (freeze-dried) powder in a sealed vial, accompanied by a batch number for full traceability. Before release, each batch is analysed by high-performance liquid chromatography (HPLC) to confirm ≥99% purity and by mass spectrometry (MS) to verify sequence identity. A batch-specific Certificate of Analysis is available on request.
For laboratory use, reconstitute the lyophilised peptide using bacteriostatic water or the solvent specified by your research protocol. Store lyophilised vials at −20°C, protected from light and moisture, and keep reconstituted solutions refrigerated at 2–8°C. Always follow your institution’s laboratory safety procedures and handle these compounds in accordance with all applicable New Zealand regulations.
These products are supplied strictly for in-vitro laboratory research purposes only. They are not medicines or dietary supplements, are not for human or veterinary use, and are not intended to diagnose, treat, cure, or prevent any disease.
All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, and not intended to diagnose, treat, cure, or prevent any disease.
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